Single server, no replication issues. DNS is fine too.
Cannot create new group policies or edit existing ones. Can write and edit files located in c:\windows\sysvol\domain\ but cannot do the same accessing through the dfs share \\somedomain.com\sysvol, but folders can be created when accessing through dfs.
Purged mmc cache too.
gpmc logs this error in event viewer when trying to save a policy-
Faulting application name: mmc.exe, version: 10.0.17763.1, time stamp: 0x176b88f0Faulting module name: GPOAdmin.dll, version: 10.0.17763.1, time stamp: 0x84e18916
Exception code: 0xc0000005
Fault offset: 0x00000000000bb4cb
Faulting process id: 0x2900
Faulting application start time: 0x01d579728f9e8483
Faulting application path: C:\Windows\system32\mmc.exe
Faulting module path: C:\Windows\System32\GPOAdmin.dll
Report Id: 399e3f06-e5a5-4860-9e16-dd641000868a
Faulting package full name:
Faulting package-relative application ID: